user tnfalpha's Blog -  - 
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Fri, Jun 22nd - 10:09AM
cell line doctrine
The cell line doctrine put forward in 1958, the Australian immunologist Burnet under the influence of the Ehrlich side-chain doctrine, put forward the doctrine of cell line selection. Doctrine to clarify the mechanism of antibody production, such as antigen recognition and immune memory and self-tolerance and autoimmune and other important immune biological phenomena explained, contributed greatly to the development of modern immunology. The basic view of the doctrine as ¢Ù that body memory a variety of cell lines in the recognition of different antigens on the cell surface of each cell line to express the same receptors that recognize the corresponding antigen; ¢Ú The antigen into the body, selectively, with the corresponding receptor cells the role of the Department of cell, activation, proliferation, differentiation into effector cells or memory cells; ¢Û embryonic stage for the immune cells of the autoantigen and autoantigen contact can be destroyed, to exclude or in an inhibitory state; ¢Ü immune cells to mutation formation and self-antigen reaction cell lines, resulting in autoimmune disease.
Related Articles: TNF-alpha
http://www.creativebiomart.net/symbolsearch_TNF.htm
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Fri, Jun 8th - 8:34AM
Tumor necrosis factor
Tumor necrosis factor detection and significance of Jain Tong, Wang Shouyi, wind, cloud (First Affiliated Hospital of Infectious Diseases) Summary of tumor necrosis factor (TNF) radioimmunoassay kits detected 84 cases of various types of hepatitis serum TNF in the serum of patients with viral hepatitisthe results showed: hepatitis serum TNF content were higher, in addition to slow to move extrahepatic other type compared with the control group, there were significant differences (P <0.01), including severe hepatitis and hepatitiscirrhosis with ascites infection to a maximum. In addition, the TNF content with the level of the patient's aminotransferase (ALT) and bilirubin (Bil,). Prompts TNF and hepatitis activity and combined infection. Keywords hepatitis, viral, human, tumor necrosis factor, radioimmunoassay (RIA) in recent years, the pathogenic role of tumor necrosis factor (tumornecrosisfactor, TNF), viral hepatitis and fulminant hepatitis in increasingly great importance , the current domestic several articles on this aspect of the reports , but their use of the L929 cell method to detect TNF activity using ELISA test, the experiment with domestic TNF radioimmunoassay kits detected 84 cases of viral hepatitis serum TNF content, the results reported below. 1.1 in case group 1 Materials and Methods: A total of 84 cases, both undergraduate hospitalized patients in February 1994 to January 1995. Male 64 cases, 20 cases of women aged 17 to 75 years, an average of 41.4 years.
Related Articles: TNF-alpha
http://www.creativebiomart.net/symbolsearch_TNF.htm
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Fri, Jun 8th - 8:27AM
Welcome to Your New Blog!
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