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Zocor (Simvastatin)
Zocor (Simvastatin) is a cholesterol- lowering medicine. It inhibits the production of cholesterol by the liver. It lowers overall blood cholesterol as well as blood LDL cholesterol levels. LDL cholesterol is believed to be the "bad" cholesterol that is primarily responsible for the development of coronary artery disease.
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Cautions
Zocor should be appointed to care for patients who abuse alcohol and / or having a history of liver disease.
In patients over age 65 receiving Zocor in controlled clinical trials, the effectiveness of the drug was the same as in the population as a whole, while there was no reliable increase in the frequency of clinical or laboratory side effects.
Patients hypercholesterolemia family, who observed the complete absence LPNP receptor, treatment Zocor normally does not give the desired clinical outcome.
Zocor has a modest effect against lowering triglycerides and did not show when hypertriglyceridemia is of paramount importance (for example, when I, IV and V types hyperlipidemia).
Zocor effective as a monotherapy or in combination with bile acids.
Laboratory indicators
Before the start of treatment for all patients are encouraged to study the functions of the liver, which should be periodically (eg once every six months) to repeat in the 1-year treatment or within 1 year after the last dose of improving. For patients whose daily dose is 80 mg, 1 study should be conducted every 3 months.
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